Study on Quality Standard for Tangui Weining Granules
- VernacularTitle:檀桂胃宁颗粒的质量标准研究
- Author:
Shuying HOU
- Publication Type:Journal Article
- Keywords:
Tangui Weining granules;
Glycyrrhizin;
Determination;
TLC;
HPLC
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2009;20(4):363-366
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a method for quality control of Tangui Weining granules. Methods TLC was used for the identification of Lignum Santali Albi and Cortex Cinnamomi. HPLC was used for the determination of Glycyrrhizin. The chromatographic conditions were as follows: Diamonsil C18(4. 6 mm ×250 mm, 5 μm)was used as a stationary phase, the mobile phase consisted of methanol-O. 2 mol/L ammonium acetate solution-acetic acid (60 : 40 : 1), the ducible, and the negative controll did not show interference. Glycyrrhizin was separated completely by HPLC and showed a good linearity in the range of 0. 1568 to 1. 568μg, r=0. 999 8, the average recovery was 99.69 %, and RSD was 0. 58 %. Conclusion TLC is simple, convenient and accurate. The method of HPLC is proved to be simple and accu-rate with a good reproducibility and can be used for the inspection of Glycyrrhizin in Tangui Weining Granules. This study provides a foundation for quality control of Tangui Weining granules.
