Study on the Preparation Technology of Tangzu Granula
- VernacularTitle:糖足颗粒的制备工艺研究
- Author:
Jiancheng TANG
;
Rongrong WANG
;
Danfei CHEN
;
Jianming PAN
- Publication Type:Journal Article
- Keywords:
Tangzu granula;
Orthogonal design;
Process research
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2009;20(4):383-385
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize the preparation process of Tangzu Granula. Methods With the paste-forming rate and total content of paeoniflorin as the indexes, the optimal water-extraction condition was screened by orthogonal design. With hydroscopicity, fluidity and formability as the indexes, the appropriate ratio of the excipient and the formula were selected. Results The optimum water-extraction condition was as follows: 10-fold water, decoction for 2 times and 1.5 hour for each time. The optimal ratio of the excipient and the formula for preparation of Tangzu granules were two proportions of the extract and three proportions of the excipient which consisted of lactose and dextrin(2 : 1, w/ w). Conclusion The technology is effec-tive, scientific, reasonable, and practical.
