Immunological enhancement effects of IL-2 on the duodenum mucosa in Gush chicken
- VernacularTitle:白细胞介素2对固始鸡十二指肠黏膜免疫增强作用
- Author:
Shusong ZHANG
;
Zhonghu LIU
;
Xiangtao KANG
;
Feng ZHAO
;
Chuanbin XIAO
- Publication Type:Journal Article
- Keywords:
iinterleukin-2 (IL-2);
duodenum;
immunohistochemistry;
SIgA;
Gushi chickens
- From:
Chinese Journal of Veterinary Science
2009;29(7):909-913
- CountryChina
- Language:Chinese
-
Abstract:
To investigate the immunological enhancement effects of IL-2 with different doses in chicken Shigella vaccine on the duodenum mucosa in Gushi chicken,parental line Gushi chicken were grouped and inoculated with Shigella vaccines including different dose of IL-2.And then the distribution and change of SIgA positive cells and its secretion in the duodenum of the chicken were observed with the immunohistochemistry technology using the Qwin image analysis system.SIgA postive cells were distributed and located primarily in inhesion membrane and enteraden cavity of the duodenum mucosa,additive IL-2 in the Shigella vaccine could increase secretion of SlgA positive cells and strengthen the immunity of the birds,in some degree.The 50 μg IL-2 in the vaccine could display a optimal immunological enhancement effect.
