Effect of hyperbaric oxygen therapy on lumbar intertransverse fusion in rabbits
- VernacularTitle:高压氧治疗对兔腰椎横突间融合的影响
- Author:
Jianhuang WU
;
Jiangnan ZHOU
;
Qiande LIAO
- Publication Type:Journal Article
- Keywords:
hyperbaric oxygen therapy;
lumbar intertransverse fusion;
bone density meas-urement;
histologic change;
rabbit
- From:
Journal of Central South University(Medical Sciences)
2009;34(7):663-666
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of hyperbaric oxygen (HBO) therapy on lumbar intertransverse fusion in rabbits. Methods Twenty-eight healthy adult female rabbits underwent lum-bar intertransverse fusion at L5～6 with autogenous iliac bone graft. They were randomly assigned into an HBO group and a control group (n=14). Rabbits were killed 6 weeks after the operation for surgical inspection, X-ray, bone density measurement and histologic analysis. Results The fusion rate of the HBO group evaluated by surgical inspection, and radiologic examination in a blind fashion significantly increased compared with that of the control group (P<0.05). Qualitative histologic as-sessment showed increased bone formation and bone maturity in the HBO group compared with the control group. Conclusion Hyperbaric oxygen therapy could improve the fusion rate of lumbar inter-transverse fusion in rabbits.
