Screening and analysis of metallo-β-lactamase -producting Pseudomonas aeruginosa in the burn ward
10.3760/cma.j.issn.1673-4130.2009.07.013
- VernacularTitle:烧伤病区产金属酶铜绿假单胞菌的筛选及分析
- Author:
Xiangming PENG
;
Yanrong LAI
- Publication Type:Journal Article
- Keywords:
Burns;
Pseudomonas aeruginosa;
beta Lactamases
- From:
International Journal of Laboratory Medicine
2009;30(7):653-654
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the resistance of metallo-β-lactamase -producting Pseudomonas aeruginosa between burn ward and other wards, so as to provide basis for reasonable use of antimicrobial agents. Methods BD Phoenix-100 bacteria identification and drug sensitivity analyzer was used to detect Pseudomonas aeruginosa and its susceptibility, and disc synergy method was used for the screening of metallo-v-lactamase -producting Pseudomonas aeruginosa. Results Of 68 strains of Pseudomonas aeruginosa, 9 strains (13.2%) were metallo-β-lactamase (MBL) positive. Among the 9metallo-β-lactamase positive strains, 7 strains were from the burn ward and 2 strains from other wards. The resistance rate of the MBL-producing strains to ceftazidime, cefotaxime, imipenem, ciprofloxacin, amikacin, gentamicin, piperacillin and aztreonam was respectively 100.0%, 100. 0%, 88.9%, 66.7%, 88.9%, 100,0%, 100.0%, and 88.9%, obviously higher than that of non-MBL-pro-ducing Pseudomonas aeruginosa. Conclusion The rate of MBL-producing Pseudomonas aeruginosa is obviously higher in burn ward than that in other wards. The resistance of MBL-producing Pseudomonas aeruginosa is high against commonly used antimicrobial agents. Clinical use of antibiotics should he based on the antimicrobial susceptibility test results.
