Analysis of antibiotic-resistant gene mecA and pathogenic genes in Staphylococcus aureus
- VernacularTitle:金黄色葡萄球菌耐药基因及致病毒素基因的研究
- Author:
Fengling WANG
;
Jing LIU
;
Qing YANG
- Publication Type:Journal Article
- Keywords:
Staphylococcus aureus;
toxic shock syndrome toxin-Ⅰ gene;
Panton-Valentine leukocidin gene
- From:
Chinese Journal of Infection and Chemotherapy
2009;09(4):280-282
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the antibiotic-resistant gene mecA and the prevalence of Panton-Valentine leukocidin (PVL) gene, toxic shock syndrome toxin (TSST-Ⅰ) gene in S. aureus. Methods A total of 74 S. aureus were collected from clinical specimens. The mecA, PVL and TSST-Ⅰ genes were detected by PCR.Results PVL gene was identified in 22 S. aureus isolates. The prevalence of PVL was 29.7% in S. aureus, 36.6% in MRSA and 21.2% in MSSA. The difference was not statistically significant (P>0.05). The prevalence of MRSA was 55.4% in 74 S. aureus. The prevalence of TSST-Ⅰ gene was 6.8%. TSST-Ⅰ gene was not detected in MSSA.Conclusions MRSA strains show highly resistant to antibiotics. PVL- and TSST-Ⅰ-positive S. aureus are more pathogenic.
