Clinical distribution and antibiotics resistance surveillance of 1 073 strains of pseudomonas aeruginosa in People's Hospital of Xinjiang Autonomous Region,2003-2007
- VernacularTitle:2003-2007年我院1 073株铜绿假单胞菌的临床分布及耐药性监测
- Author:
Juan LI
;
Zhiwei LI
- Publication Type:Journal Article
- Keywords:
Pseudomonas aeruginosa;
drug resistance;
infection
- From:
Chinese Journal of Infection and Chemotherapy
2009;09(4):286-288
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the pattern of antibiotic resistance in 1 073 strains of Pseudomonas aeruginosa in People's Hospital of Xinjiang Autonomous Region during 2003-2007. Methods Automated microbe analyzer (VITEK32) was used to analyze antibiotic susceptibility by means of GNS drug sensitivity card and Kirty-Bauer method. Results In recent five years, 1 073 strains of P. aeruginosa were isolated from respiratory specimens, most of which were from ICU, respiratory ICU and surgery ICU (57.8%). Among the 16 antibiotics tested, these strains showed the lowest resistance (17.0%) to cefoperazone-sulbactam, followed by meropenem (18.5%), amikacin (19.6%), imipenem (24.2%), cefepime (25.7%), piperacillin-tazobactam (35.7%) and ceftazidime (36.7%). Although the resistance to cefoperazone-sulbactam and ceftazidime was relatively lower, the prevalence of intermediate strains was relatively higher, 15.2% and 12.5% respectively. Conclusions The antibiotic resistance surveillance Results of five consecutive years indicate that P. aeruginosa was one of the most common pathogens in this hospital associated with serious issue of antibiotic resistance.
