Comparability of sensory retinal thickness measured by different OCTs to histological studies in rabbit eyes
- VernacularTitle:两种相干光断层扫描仪测量兔眼视网膜厚度和组织学检查的对比研究
- Author:
Lina HUANG
;
Ning FAN
;
Hongbo CHENG
;
Mingying LAI
;
Jun ZHAO
- Publication Type:Journal Article
- Keywords:
optical coherence tomography;
retina;
experimental study
- From:Ophthalmology in China
2009;18(4):239-242
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study correlation of the retinal nerve epithelium layer thickness measured with different optical coher-ence tomography (OCT) in vivo with histological measurement. Design Experimental study. Participants 15 rabbit eyes. Methods The retina measurement position of 15 rabbit eyes were marked by laser, and then were scanned by OSE-1800 OCT and Stratus OCT. Reti-nal nerve epithelium layer thickness was measured in retinal histological shdes of rabbit eyes. The results measured with three methods were compared and linear regression analyses were done with SPSS11.5 software. Results The average retinal nerve epithelium layer thickness measured with OSE-1800 OCT, Stratus OCT and histological method were 119.5±7.4, 118.0±5.6, and 116.3±8.8μm respec-tively(P=0.292). Retinal nerve epithelium layer thickness measured with both OCT instruments had the best correlation (r=0.914, P= 0.000), and the thickness measured with Stratus OCT and histological method had the better correlation (r=0.872, P=0.001), and the thickness measured with OSE-1800 OCT and histological method had the significant correlation (r=0.833, P=0.002). Conclusions The retinal nerve epithelium layer thickness measured with different OCTs in vivo correlate well with histomorphometry, and the measure-ment of both OCT instruments are accurate. (Ophthalmol CHN, 2009, 18: 239-242)
