Biomarkers of lung cancer micro-metastasis and their detection
10.3760/cma.j.issn.1673-422X.2011.01.013
- VernacularTitle:肺癌微转移相关标记物及其检测
- Author:
Liang MA
;
Guoxin MAO
- Publication Type:Journal Article
- Keywords:
Lung neoplasms;
Micro-metastasis;
Tumor markers,biological
- From:
Journal of International Oncology
2011;38(1):39-42
- CountryChina
- Language:Chinese
-
Abstract:
Micrometastasis is small metastasis at the cellular and molecular level. Early detection of micrometasis through tumor markers can improve the accuracy of TNM staging, prognosis and subsequently treatment for lung cancer patients. Currently, a number of markers with good specificity and sensitivity have been found, including CK19 mRNA, Lunx mRNA, MUC1 mRNA and GPRP mRNA. These markers can be detected using methods such as RT-PCR, immunohistochemistry and western blot.
