Targeted therapy and its application on gastrointestinal stromal tumor
- VernacularTitle:靶向治疗在胃肠道间质瘤中的应用
- Author:
Yingqiang SHI
;
Kai HUANG
;
Zhiyu CHEN
- Publication Type:Journal Article
- Keywords:
gastrointestinal stromal tumor;
imatinib;
targeted tharapy
- From:China Oncology
2009;19(6):409-411
- CountryChina
- Language:Chinese
-
Abstract:
Targeted therapy has gradually become the focus in the treatment of tumor, with the emerge of more and more targeted drugs which has brought the treatment of tumor into a new era. Imatinib, the tyrosine kinase inhibitor, is one of the important types of targeted therapy, has become the standard of care in adjuvant therapy of gastrointestinal stromal tumor(GIST) with extraordinary effects. However, the questions are still on debate incluing the optimal way to evaluate treatment results, the treatment duration, whether it can be intermitted or not, second line therapy for imatinib-intolerance or -resistance and the combination with surgery.
