The neuroprotective effect of hypoxia-inducible factor-1 and vascular endothelial growth factor in cerebral ischemia
10.3760/cma.j.issn.1673-4165.2011.02.013
- VernacularTitle:低氧诱导因子-1和血管内皮生长因子在脑缺血中的神经保护作用
- Author:
Jianhua FENG
;
Yongjie LUO
- Publication Type:Journal Article
- Keywords:
Brain ischemia;
Hypoxia-inducible factor 1;
Vascular endothelial growth factors
- From:
International Journal of Cerebrovascular Diseases
2011;19(2):142-146
- CountryChina
- Language:Chinese
-
Abstract:
Hypoxia-inducible factor(HIF)is a pivotal transcription factor for hypoxic response.This article reviews the related characteristics of HIF-1 and its target genes vascular endothelial growth factor and the neuroprotective mechanisrms in cerebral ischemia.