Progress in inflammatory cardiomyopathy
10.3760/cma.j.issn.1673-4408.2011.02.015
- VernacularTitle:炎症型心肌病研究进展
- Author:
Yan SUN
- Publication Type:Journal Article
- Keywords:
Inflammatory cardiomyopathy;
Immune;
Myocarditis
- From:
International Journal of Pediatrics
2011;38(2):141-143
- CountryChina
- Language:Chinese
-
Abstract:
Viral myocarditis can cause severe myocardial injury and even acute heart failure, then evolve into dilated cardiomyopathy, known as inflammatory cardiomyopathy. Immune reaction plays a key role in the transformation from viral myocarditis into dilated cardiomyopathy, including virus RNA continuous replication,immune-mediated injury, cellular apoptosis, other cellular immune response , myocardial antibodies and other humoral immune response. In the clinical treatment, besides anti-heart failure and cardiac nutrition, the use of ribavirin, α1-receptor blockers, β-receptor blockers, calcium channel blockers, angiotensin converting enzyme inhibitors and spironolactone should be emphasized.