CT-guided interstitial implantation of ~(125)I seeds for non-small cell lung cancer
- VernacularTitle:CT导向下~(125)I粒子组织间植入治疗非小细胞肺癌
- Author:
Guiyuan TIAN
;
Lei ZHANG
- Publication Type:Journal Article
- Keywords:
non-small cell lung carcinoma;
radioactive seed;
brachytherapy;
interventional therapy
- From:
Journal of Interventional Radiology
2009;18(9):704-707
- CountryChina
- Language:Chinese
-
Abstract:
Objective To discuss the technique, therapeutic effect and complications of CT-guided interstitial implantation of ~(125)I seeds for the treatment of non-small cell lung carcinoma (NSCLC). Methods With the help of treatment planning system, CT-guided interstitial implantation of ~(125)I seeds was performed in 21 patients with pathologically-proved NSCLC. Multi-plane implanting technique was adopted and ~(125)I seeds of (0.5 -0.8) mCi were placed at intervals of (1.0-1.5) cm. Checkup CT scan was carried out immediately after the procedure to make sure that the seeds were satisfactorily distributed. Follow-up CT scanning was made (2-6) months after the treatment to survey the distribution of the seeds within the tumor. The curative effect and complications were also evaluated and observed. The patients were followed for 12 months. Results Of 21 cases, complete remission was seen in 7, obvious remission in 12 and partial remission in 2. The one year survival rate was 90.5% (19/21). Complications included pneumothorax (n = 6) and hemoptysis (n = 2). No serious complications or treatment-related radiation injuries occurred. Conclusion CT-guided interstitial implantation of ~(125)I seeds is a safe and effective treatment for NSCLC with reliable short-term therapeutic effect.
