Preparation and characterization of silk fibroin/hydroxyapatite porous composite materials
10.3969/j.issn.1673-8225.2009.34.044
- VernacularTitle:羟基磷灰石/丝素蛋白复合多孔材料的制备及其表征
- Author:
Shenzhou LU
;
Jiajia LIU
;
Shuqin YAN
;
Jianbing LIU
;
Mingzhong LI
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2009;13(34):6789-6792
- CountryChina
- Language:Chinese
-
Abstract:
Silk fibroin (SF) and hydroxyapatite (HA) composite powders were synthesized from CaO, H3PO4 and SF solution on the principle of neutralization. SF/HA porous materials were prepared through adding silk short fibers and NaCI particles as reinforcing material and pore-forming agent respectively by isostatic compaction. The structure and mechanical properties of the SF/HA porous materials were investigated. Results indicated that short silk fibers in it could markedly enhance flexural strength and flexural breaking energy. The average pore diameter and porosity could be regulated from 64 μm to183 pm and from 55% to 75% respectively by adding pore-forming agent.