Establishment and analysis of three-dimensional finite element model based on tail-suspended rat experiment
10.3969/j.issn.1673-8225.2009.39.012
- VernacularTitle:基于大鼠尾部悬吊实验的三维有限元模型建立与分析
- Author:
Qi LI
;
Wentao JIANG
;
Yubo FAN
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2009;13(39):7657-7660
- CountryChina
- Language:Chinese
-
Abstract:
By using three-dimensional finite element analysis method, the necessity of tail joints in the establishment of finite model specifically for the widely used tail-suspended rat experiments in weightlessness simulation was explored. A weightlessness tail-suspended three-dimensional finite element rat model was established using CT scan and Abaqus software, and the computation and analysis were conducted using the same model. The stress distribution and displacement in tail, lumbar spine, pelvis and femur of a tail-suspended rat both with and without cartilage were simulated and calculated.The results showed that stress distribution and displacement of tail-suspended rat were quite different between rats with cartilage and without cartilage, which affected the calculation precision of the model. Accordingly the consideration of articular cartilage in establishing the tail-suspended three-dimension finite element rat model is quite necessary,In addition, the asymmetry of pelvis stress distribution of tail-suspended rat suggests that the degree of balance of tail-suspended rat will affect the stress distribution in rats.
