A Case of Doxifluridine-Induced Multiple Atypical Moles on the Palm and Sole of a Patient Taking Immunosuppressive Agents.
- Author:
Woon Kyong CHUNG
1
;
Seong Min KANG
;
Do Young RHEE
;
Sung Eun CHANG
;
Mi Woo LEE
;
Jee Ho CHOI
;
Kee Chan MOON
Author Information
1. Department of Dermatology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. 1052_hihi@hanmail.net
- Publication Type:Case Report
- Keywords:
5-Fluorouracil;
Acral;
Doxifluridine;
Hyperpigmentation;
Mole
- MeSH:
Adult;
Female;
Floxuridine;
Fluorouracil;
Humans;
Hyperpigmentation;
Immunosuppressive Agents;
Prodrugs;
Pyrimidines
- From:Korean Journal of Dermatology
2008;46(9):1257-1261
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Doxifluridine is a pyrimidine derivative and is activated to 5-fluorouracil by pyrimidine phosphorylase. Multiple acral hyperpigmented macules have been reported in patients treated with systemic 5-fluorouracil or some of its prodrugs. However, there have been no reports of this adverse event being induced by doxifluridine. Herein we present a 42-year-old woman with multiple pigmented lesions on the palm and sole after chemotherapy with oral doxifluridine.
