Advancing research on relationship between stromal cells and the development of tumor
- VernacularTitle:基质细胞与肿瘤发生发展之间的关系
- Author:
Lei ZHANG
;
Xiaomin WANG
- Publication Type:Journal Article
- Keywords:
tumor microenvironment;
stromal cell;
MMPS;
tumor
- From:
China Oncology
2009;19(10):788-792
- CountryChina
- Language:Chinese
-
Abstract:
Stromal cells are one of the important components of tumor mieroenvironment, which plays an oncogenic role in tumorigenesis. Stromai cells and their products can transform adjacent tissues in the absence of pre-existing tumor cells by inciting phenotypic and genomic changes in the epithelial cells. The research on the tumor-associated-stromal cells will be benefit in clarifying the mechanisms of carcinogenic lesions and investigating more effective therapy methods.
