Advance in the study of microRNA in tumor metastasis
- VernacularTitle:MicroRNA和肿瘤转移关系的研究进展
- Author:
Minyan XING
;
Zan SHEN
- Publication Type:Journal Article
- Keywords:
miRNA;
tumor;
metastasis
- From:
China Oncology
2009;19(10):793-796
- CountryChina
- Language:Chinese
-
Abstract:
Within the past few years, studies on MicroRNA (miRNA) and tumor metastasis have become the focus of attention. Multiple lines of evidence demonstrated the involvement of specific miRNAs in tumor metastasis, which can negatively regulate the expression of target mRNA and post-transcriptionally control gene expression. Metastasis is the key indicator of tumor malignancy and is the main reason of death of the tumor patients, so how to prevent and control it is important to increase the survival of the tumor patients. This review summarized the recent progress on the research field of miRNA and its association with tumor metastasis.