Syndrome of Inappropriate Antidiuretic Hormone Secretion in Small Cell Lung Cancer
10.3969/j.issn.1000-8179.2009.21.016
- VernacularTitle:小细胞肺癌合并抗利尿激素异常分泌综合征研究进展
- Author:
Jian JIANG
;
Jun LIANG
- Publication Type:Journal Article
- Keywords:
Small cell lung cancer (SCLC);
SIADH;
Hyponatremia
- From:
Chinese Journal of Clinical Oncology
2009;36(21):1256-1259
- CountryChina
- Language:Chinese
-
Abstract:
Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH) was a common complica-tion of small cell lung cancer (SCLC). Recent studies have suggested that the origin of this disease is related to seceration of tumor cells and application of medecine. The inappropriate antidiuretic hormone secretion can lead to disturbance of metabolism of water and sodium, resulting in hyponatremia. Because the symp-toms are atypical, the diagnosis is difficult. Many cases are misdiagnosed or misseddiagnosed. The primary tumor must be treated and the restriction of water intake is the main and effective method to deal with SIADH. Prognosis of SCLC patients with SIADH is poor in most reports.
