Roles of interleukins in carcinogenesis and development of gastric cancer
- VernacularTitle:白细胞介素在胃癌发生和发展中的作用
- Author:
Benyan ZHANG
;
Xiaolong JIN
- Publication Type:Journal Article
- Keywords:
gastric cancer;
interleukins;
inflammation
- From:
Journal of Shanghai Jiaotong University(Medical Science)
2009;29(11):1387-1390
- CountryChina
- Language:Chinese
-
Abstract:
Helicobacter pylori (H. Pylori) infection has been an established risk factor for gastric cancer identified by World Health Organization. H. Pylori triggers chronic inflammation of gastric mucosa and induces host cells to release various cytokines, some of which might lead normal epithelial cells to transfer to gastric cancer. Expression of interleukins in gastric mucosa experiences significant changes after H. Pylori infection. Interleukins play different roles in carcinogenesis and development of gastric cancer. This article briefly reviews the research advances of roles of interleukins in carcinogenesis and development of gastric cancer.
