Effect of midkine, a newly heparin - binding cytokine, on cardiovascular functions
- VernacularTitle:新型肝素结合细胞因子midkine的心血管作用
- Author:
Xiaoran LIU
;
Lin YE
;
Lan MA
;
Chaoshu TANG
- Publication Type:Journal Article
- Keywords:
Midkine;
Angiogenesis;
Cardiovascular system;
Apoptosis
- From:
Chinese Journal of Pathophysiology
2009;25(11):2221-2224
- CountryChina
- Language:Chinese
-
Abstract:
Midkine (MK) , a newly discovered heparin - binding growth factor, promotes growth, survival, and migration in various cells. Meanwhile, MK stimulates statistically significant forms in new arterioles and capillaries, causes vascular remodeling, prevents ischemia myocardial cells from injury via inhibiting apoptosis. MK also regulates the level of blood - fat.In general, MK plays key roles in cardiovascular diseases.
