Effects of anaerobic interval training on free radical metabolism of skeletal muscle,myocardium and liver in rats
10.3969/j.issn.1673-8225.2009.46.028
- VernacularTitle:无氧间歇训练对大鼠骨骼肌、心肌、肝脏自由基代谢的影响
- Author:
Xiufang QIAO
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2009;13(46):9129-9132
- CountryChina
- Language:Chinese
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Abstract:
BACKGROUND:As an import training method,anaerobic interval training is widely applied.However,systematically studies regarding the effects of this training on free radical metabolism and antioxidant system are few.OBJECTIVE:To study the effects of anaerobic interval training on free radical metabolism in rats.DESIGN,TIME AND SETTING:A randomized controlled animal experiment was performed at the laboratory of exercise physiology.Xuzhou Normal University from March to May 2008.MATERIALS:A total of 32 male SD rats,weighing 230-270 g,were randomly divided into four groups:sedentary control,interval training control,interval exercise immediate,and interval training immediate,with 8 animals in each group.METHODS:No training was performed in the sedentary control group.Rata in the interval training control and interval training immediate groups were run with speed of 26.8 m/min for 1 minute at the gradient of 10°,then 5 m/min at gradient of 0°,followed by 3 minutes rest,this process was kept for successive 20 times per day,5 days per week,for 6 weeks.Rats in the interval exercise immediate group were fun once at the last day of the 6~(th) week.MAIN OUTCOME MEASURES:Rats were sacdficed under anesthesia after 6 weeks,the super oxide dimutese(SOD),glutathione peroxidase(GPX),catalase(CAT)and malonaldehyde(MDA)contents in skeletal muscle,myocardium and liver were tested.RESULTS:①After 6-week training,SOD activity in each tissues of the training groups were obviously greater than that of the interval exercise immediate group(P＜0.05).②Compared to the sedentary control group,the GPX activity in quadriceps femons and myocardium of the interval exercise immediate group was dramatically smaller(P＜0.05),but the MDA content was greater (P＜0.05),with higher CAT levels in quadnceps femoris and livers(P＜0.05).③Compared to the interval exercise immediate group,the GPX activity of the interval training immediate group was notably higher in the quaddceps femofis and myocardium (P＜0.05),MDA level was lower,and the CAT levels increased remarkably in quaddceps femoris and myocardium(P＜0.05).CONCLUSION:Anaerobic interval training can induce adaptive change of antioxidant enzymes and enhance the ability of cleaning free radical.
