Structure,function,and metabolism of Lamin A
10.3969/j.issn.1673-8225.2009.46.037
- VernacularTitle:核纤层蛋白Lamin A的结构及功能和代谢特征
- Author:
Yanchao MA
;
Shousheng XU
;
Yue ZHOU
;
Ruiyuan WANG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2009;13(46):9167-9170
- CountryChina
- Language:Chinese
-
Abstract:
Lamin A,which is an important skeleton protein in the cell nucleus,can play an important role in maintaining the morphological structures of the cells.This article summarizes the location of LMNA gene in the chromosome,the shape and the structum of lamin A protein;the different diseases of the body which result from the mutations and deletions of LMNA gene in different sites;the differentiation functions of myoblast in which lamin A is involved:degradation of lamin A that may be promoted by Caspase-6;theexpression of lamin Athatmay bepromoted by NFAT5.
