Advances of anti-osteoporosis drugs in clinical application
10.3969/j.issn.1673-8225.2009.46.036
- VernacularTitle:抗骨质疏松药物临床应用的进展
- Author:
Sicheng WANG
;
Xuehua YANG
;
Jiacan SU
;
Liehu CAO
;
Zhuodong LI
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2009;13(46):9163-9166
- CountryChina
- Language:Chinese
-
Abstract:
Osteoporosis is a common disease in the elderly. As studies on its causation and pathogenic mechanism deepened in recent years,there appeared many anti-osteoporotics and many of them had been widely used in clinic. However,none of them was found to be able to completely replace other drugs to achieve satisfactory effect in clinical applications. They all have certain defects. In this paper,three types of drugs including bone resorption inhibitors,bone mineralizers and bone formation accelerators,were analyzed in terms of their mechanisms of action,advances in clinical application as well as their side effects,so as to guide the clinical choice and combination of drugs targeted to avoid serious side effects and to seek for the direction of further study.
