The value and limitation of ultrasound test-appraised endothelial function of brachial artery in elderly diabetic patients

VernacularTitle:超声检查评价老年糖尿病患者肱动脉内皮功能的价值与局限性
Author: Wei QIU ; Wenhua WANG
Publication Type:Journal Article
Keywords: Diabetes mellitus,type 2,Elderly patients; Flow-mediated vasodilation
From: Chinese Journal of Diabetes 2009;17(12):921-922
CountryChina
Language:Chinese
Abstract: Objective To investigate the value and limitations of ultrasound determination-evaluated brachial artery endothelial function in elderly diabetic patients. Methods High-resolution two-dimensional ultrasound was used to determine brachial artery(BA) flow-mediated vasodilation(FMD) during reactive hyperemia. Endothelial function was evaluated by FMD in 67 elderly patients with type 2 diabetes. Results In diabetes versus normal control group,the BA diameter and flow velocity showed no significant difference (P＞0.05) at basal state,but showed significant decreases (P＜0.05) after reactive hyperemia. Single-factor correlation analysis showed that FMD was in negative correlation with disease course, TG, ISI and age (r=-0.2357,-0.2215 and -0.3256, -0.2415,(all P＜0.05～0.01),and showed no correlation of FMD with BMI, TC, FBG, HbA1c, FIns. Conclusions FMD has a value in evaluating the flow-mediated endothelial dysfunction in older T2DM patients, while our analysis of the results should consider the patient's age, gender, race, disease course, blood lipids and other factors.