Research progress in molecular mechanism of the pharmacological actions of emodin
- VernacularTitle:大黄素药理作用的分子机制研究进展
- Author:
Han LIU
;
Yun GAO
- Publication Type:Journal Article
- Keywords:
emodin;
pharmacological actions;
molecular mechanism;
ion transportation;
inflammatory factor;
apoptosis
- From:
Chinese Pharmacological Bulletin
2009;25(12):1552-1555
- CountryChina
- Language:Chinese
-
Abstract:
Emodin is the main effective monomer of Rhubarb, which has a variety of pharmacological actions and valuable clinical applications.Recently, there are many reports about molecular mechanisms of emodin pharmacological actions,and they givehighly attention on the dephlogisticating and antineoplastic effects. These effects are achieved through affecting the concentration and transportation of ions, resisting of oxidation and free radical, and affecting the secretion of inflammatory factor and the enzyme activity and apoptosis and so on. This article summarizes the reports and hopes to provide theoretical basis for the practical application.
