Prognostic Value of ~(99m)Tc-Sestamibi Gated Myocardial Perfusion Imaging in Coronary Artery Disease Patients
10.3969/j.issn.1000-3614.2009.03.005
- VernacularTitle:~(99m)锝-甲氧基异丁基异腈门控心肌灌注显像在冠心病预后评估中的价值
- Author:
Haiyan XU
;
Dianfu LI
;
Jianlin FENG
;
Xu CHENG
;
Jianhua LI
- Publication Type:Journal Article
- Keywords:
Gated myocardial perfusion imaging;
Coronary artery disease;
Prognosis
- From:
Chinese Circulation Journal
2009;24(3):174-177
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To determine the long-term prognostic value of ~(99m)Tc-sestamibi (MIBI) Gated myocardial perfusion imaging(G-MPI)in patients with coronary artery disease.Methods: A total of 1345 consecutive symptomatic coronary artery disease patients who underwent ~(99m)Tc-MIBI G-MPI were studied.1250 patients were followed-up by telephone interview, the median follow-up time was 26.7±13.6 months.Events were defined as cardiac death, nonfatal myocardial infarction and revascularization by coronary artery bypass graft or percutaneous coronary artery intervention.Results: Cox regression analysis indicated that summed stress score (3.8±6.1,χ~2=67.25), summed different score (1.1±3.0,χ~2=21.09) and left ventricular ejection fraction (LVEF) (0.667±0.097,χ~2=42.26) were independent predictive factors of cardiac events (P<0.01).Kaplan-Meier analysis indicated that cardiac event free survival was significantly lower in the patient with LVEF≤50%.Conclusion: In Patients with symptomatic coronary artery disease, the summed stress score, summed rest score, summed different score and LVEF had prognostic value, and low LVEF indicated worse prognosis.
