The relationship between femur and serum calcium and phosphorus content in osteoporosis

VernacularTitle:骨质疏松症大鼠股骨中钙、磷与血清中钙、磷含量的相关性研究
Author: Baomin LU ; Qingsheng GUO
Publication Type:Journal Article
Keywords: Osteoporosis/ME; Calcium/ME; Phosphorus/ME; Femur/ME; Serum/ME
From: Journal of Chinese Physician 2011;13(1):58-60
CountryChina
Language:Chinese
Abstract: Objective To study the relationship between femur and serum calcium and phosphorus content in rat with osteoporosis. Methods We developed animal models with rat experienced bilateral oophorectomy and used inductively coupled plasma atomic emission spectrometry (ICP-AES) to determine calcium and phosphorus content in femur and serum of experimental group as well as control group. Results Calcium and phosphorus contents in femur in experimental group were significantly lower than that in control group[Ca: (218.59 ± 10.43) mg/L vs (253.32 ±7.54)mg/L;P:( 127.82 ±3.71 )mg/L vs ( 142. 18 ±5.99 ) mg/L, P ＜0. 01], but in serum experimental group it was significantly higher than that in control group [Ca: (99.45 ±0.76)mg/L vs (97.56±0.80) mg/L;P: (67.68 ± 1.63) mg/L vs (60.00 ± 1.18) mg/L,P ＜0. 01]. Conclusion Femur calcium and phosphorus levels were significantly reduced, which was related to the increase of serum calcium and phosphorus content, and it was one of the causes of osteoporosis.