C-reactive protein and atherosclerotic inflammation
- VernacularTitle:C-反应蛋白与动脉粥样硬化炎症的关系
- Author:
Suowen XU
;
Peiqing LIU
- Publication Type:Journal Article
- Keywords:
C-reactive protein;
Atherosclerosis;
Inflammation;
Acute coronary syndrome
- From:
Chinese Journal of Pathophysiology
2009;25(12):2487-2490
- CountryChina
- Language:Chinese
-
Abstract:
Inflammation plays a pivotal role in atherogenesis. In addition to being a potent predictive and prognostic marker for major cardiovascular events, recent evidence indicates that C-reactive protein (CRP) might directly promote atherogenesis by exerting direct effects on vascular cells. Thus, CRP will become important novel pharmaceutical targets for the treatment of atherosclerosis. This review presents an overview of the current knowledge about the pathological role of CRP in atherosclerosis initiation and progression.