Clinical analysis of nervous system non-Hodgkin's lymphoma resembling to inflammatory diseases
- VernacularTitle:疑似炎症性疾病的神经系统非霍奇金淋巴瘤
- Author:
Ziyi CHEN
;
Jinsheng ZENG
;
Xiuling HANG
;
Tingsheng PENG
;
Ling CHEN
- Publication Type:Journal Article
- Keywords:
Non-Hodgkin lymphoma Nervous system Biopsy
- From:
Chinese Journal of Nervous and Mental Diseases
2009;35(12):738-741
- CountryChina
- Language:Chinese
-
Abstract:
Objective To characterize the manifestations of non-Hodgkin's lymphoma in nervous system with in-flammation-like presentation. Methods We reviewed clinical and laboratory data obtained from 3 cases of non-Hodgkin's lymphoma in nervous system with inflammation-like presentation.Those data include clinical manifestations,CSF examina-tions neuroimaging,pathology of biopsies,treatment and prognosis.Results The clinical manifestations of NHL in nervous system were variable and the findings of cerebrospinal fluid and imaging were not characteristic.Parital relief of symptoms by steroid cortisone could be achieved in some cases which maght further increased the difficulty in differentiating NHL from CNS inflammation.Several signs including no evidence of CNS inflammation,multiple organ involyements,especially the organ involvements outside CNS,and deterioration after a transient relief of symptoms by steroid cortisone,strongly suggest the possibility of NHL.Condusions We should increase physicians'awareness to NHL to reduce the misdiagnosis even though the final diagnosis relies on pathological examination.
