Effect of Restraint and Watered Stress of Different Durations on Gastric Empting in Rats
- VernacularTitle:不同时程束缚水浸应激对大鼠胃排空的影响
- Author:
Dan ZHANG
;
Zhiwei XIA
;
Yajing HAN
- Publication Type:Journal Article
- Keywords:
Chronic restraint;
Watered stress;
Gastric emptying: Rats
- From:
Acta Laboratorium Animalis Scientia Sinica
2009;17(6):415-418
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of restraint and watered stress of different durations on the gastric empting in rats. Methods 48 male SD rats (weight ±150 g) were divided randomly into 6 groups with 8 in each. The experimental rats were restrained and watered in 23℃ water box for 1 h/d, while the controls were free. The body weight, general conditions and behavioral indexes of the rats were observed and recorded. The gastric empting rate was measured in rats with semi-solid diet after 3 d,7 d and 28 d during the statistically significant differences among different groups of different stress groups,and between the 3 d test group and 3 d control group. The gastric empting rate was higer in the 7-day test than in 7 d controlled group, lower in the 28 d test group than 28 d control group. Conclusion Different chronic stress can cause changes of gastric empting rate. With the prolonging of stress time, the empting rate is rising and then decending.
