A Meta-analysis of the risk factors of delirium in ICU
10.3761/j.issn.0254-1769.2010.01.002
- VernacularTitle:ICU谵妄危险因素的Meta分析
- Author:
Jie HUANG
;
Qian XIAO
;
Ying WU
;
Chunli WANG
;
Peng YUE
;
Xin YANG
- Publication Type:Journal Article
- Keywords:
Delirium;
Risk Factors;
Intensive Care Units;
Meta-Analysis
- From:
Chinese Journal of Nursing
2010;45(1):6-9
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify the risk factors of delirium in ICU by Meta-analysis. Methods Quality of the studies was assessed in terms of study design, definitions of main variables, statistics, and bias control. Analysis of sensitivity and heterogeneity were performed and cumulative effects were calculated using either fixed or random effects models by RevMan 4.2.Results Ten studies met all inclusive and exclusive criteria. Simple sizes range from 100 to 3308. Twenty-one risk factors of delirium in ICU were involved, but only alcohol abuse, respiratory disease, infection, APACHE Ⅱ,elevated level of serum urea nitrogen, hyponatremia, hyperbilirubinemia and using sedatives were identified as having a cumulative effect on delirium in ICU. Conclusions Infection, abnormality or disturbance of metabolism and intoxication or acute withdrawal from drug or alcohol are independent predictors of delirium in ICU, while advanced age and hypoxemia, which are commonly considered as independent risk factors of delirium in ICU, are still inconclusive.
