Liver failure after partial hepatic resection: pathophysiology,risk factors and treatment
10.3760/cma.j.issn.1007-8118.2011.04.002
- VernacularTitle:肝切除术后肝功能衰竭:病理生理、危险因素与临床治疗
- Author:
Yitao DING
;
Chunping JIANG
- Publication Type:Journal Article
- Keywords:
Hepatectomy;
Hepatic failure;
Treatment
- From:
Chinese Journal of Hepatobiliary Surgery
2011;17(4):279-282
- CountryChina
- Language:Chinese
-
Abstract:
Liver failure is a dreaded and often fatal complication that sometimes follows partial hepatectomy.This article reviews the pathophysiology, risk factors and treatment of post-resectional liver failure (PLF). An inadequate quantity or quality of residual liver mass are the key event in its pathogenesis. The major risk factors are small remnant liver volume (RLV), excessive blood loss or transfusion, ICGR15 of greater than 20%, and F4/F3 liver cirrhosis. It is essential to identify these risk factors during the pre-operative assessment. Preventive measures should be applied whenever possible as options of curative treatment for PLF are limited. Artificial liver and/or liver transplantation are the important treatment alternatives for hepatic failure after hepatectomy.
