Colorectal carcinoma and DNA methylation
- VernacularTitle:结直肠癌与DNA甲基化
- Author:
Minji LIU
;
Shourong SHEN
- Publication Type:Journal Article
- Keywords:
colorectal neoplasm;
epigenetics;
DNA methylation
- From:
Journal of Central South University(Medical Sciences)
2009;34(12):1266-1270
- CountryChina
- Language:Chinese
-
Abstract:
Epigenetic regulation involved in eukaryotic gene expression plays an important role in the progression of colorectal cancer. Colorectal cancer epigenetics is evolved in DNA methylation which is associated with the activation of oncogene and inactivation of tumor suppressor gene. The potential reversibility of DNA methylation offers exciting opportunities for therapy and diagnosis of colorectal carcinoma.
