Nanometer silver dressing plus recombinant bovine basic fibroblast growth factor gel for residual burn wounds
10.3969/j.issn.1673-8225.2009.47.036
- VernacularTitle:纳米银敷料结合重组牛碱性成纤维细胞生长因子凝胶治疗烧伤残余创面
- Author:
Zhiyong WENG
;
Ruohong DING
;
Bin HAN
;
Zhenghua CHEN
;
Zhenghua XIE
;
Jun TANG
;
Fajun KE
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2009;13(47):9357-9360
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To investigate the curative effects of nanometer silver dressing and recombinant bovine basic fibroblast growth factor gel on burn residual wounds.METHODS: Forty burn patients with residual wounds because of deep second degree burn and full-thickness burn, were randomly divided into control group and management group. There were 20 patients in both groups. The patients of management group were treated by nanometer silver dressing and recombinant bovine basic fibroblast growth factor gel. The patients of control group were treated by saline and paraffin absorbent gauze. Healing time, wound healing rates at different time points,cases of infected wound and results of bacterial culture before and 7 days following treatment, and drug adverse reaction were recorded.RESULTS: The healing time of management group was significantly shorter than the control group (P < 0.01). The wound healing rates of management group was significantly higher than the control group at different time points (P< 0.01). The cases of infected wound was significantly fewer than the control group after treating (P < 0.01). The pathogenic bacteria detection rate was significantly lower than the control group after 7 days (P < 0.01).CONCLUSION: There was better antibacterial activity, decurtating the healing time when the management of nanometer silver dressing and recombinant bovine basic fibroblast growth factor gel on burn residual wounds were put into practice.
