Mathematical models for bulk erosion type drug delivery systems
10.3969/j.issn.1673-8225.2009.52.029
- VernacularTitle:本体溶蚀型药物传输系统的数学模型
- Author:
Hongze LIU
;
Min QI
;
Zhiyong WEI
;
Libo LIU
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2009;13(52):10340-10344
- CountryChina
- Language:Chinese
-
Abstract:
Bulk erosion type biodegradable materials play an important role in pharmaceutics.However,the instability of carriers affects drug delivery systems critically,and complicates their drug release kinetics.Among these problems,how degradation and erosion affect drug release patterns becomes a focus.Mathematical models facilitate to understand complex pharmaceutical drug release patterns,and are easily applied in structure design of drug delivery systems and to predict their drug release kinetics.This paper reviews the degradation and erosion patterns,drug release mechanisms,and the recent research of mathematical models.
