The Target Plasma Concentration of Propofol Required to Insert a Laryngeal Mask Airway without Muscle Relaxant Use.
10.4097/kjae.2003.44.1.18
- Author:
Jong Hoon YEOM
1
;
Sang Yoon CHO
Author Information
1. Department of Anesthesiology, School of Medicine, Hanyang University, Seoul, Korea. chosy@hanyang.ac.kr
- Publication Type:Original Article ; Randomized Controlled Trial
- Keywords:
Bispectral index;
laryngeal mask airway;
propofol;
target-controlled infusion
- MeSH:
Anesthesia;
Hemodynamics;
Humans;
Laryngeal Masks*;
Plasma*;
Propofol*;
Reflex;
Unconsciousness
- From:Korean Journal of Anesthesiology
2003;44(1):18-23
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: We evaluated laryngeal mask airway (LMA) insertion conditions, hemodynamic changes and bispectral index (BIS) responses during the induction of anesthesia with target controlled infusion (TCI) of propofol. METHODS: Ninety patients (ASA 1 or 2, 18-64 years) were allocated randomly to receive an infusion to achieve and maintain target blood concentration of a 4, 5 and 6micro gram/ml. LMA was inserted after loss of consciousness. LMA insertion conditions, hemodynamic and BIS responses were evaluated. RESULTS: Loss of consciousness and LMA insertion were more rapid in patients with propofol target blood concentration of a 6micro gram/ml than at the other concentrations. Also, full attenuation of larygeal reflexes on the first try was greater in the 6micro gram/ml group than the other groups. CONCLUSIONS: We conclude that propofol administration at a target blood concentration of 6micro gram/ml allow successful insertion of LMA without major hemodynamic changes.
