Preparation and biocompatibility of poly ester-amide electrospinning nanofiber membrane
10.3969/j.issn.1673-8225.2009.51.008
- VernacularTitle:聚酯酰胺静电纺纳米纤维膜的制备及其生物相容性
- Author:
Xiaofeng LIU
;
Xiumei MO
;
Changlong HE
;
Hongsheng WANG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2009;13(51):10045-10048
- CountryChina
- Language:Chinese
-
Abstract:
The poly ester-amide (PEA) nanofiber membrane was prepared by electrospinning and the surface topography of nanofiber membrane was observed by scanning electron microscope (SEM). It was found that with the increasing of spinning fluid concentration from 10% to 20%, the diameter of prepared fibers was increased from 180 nm to 305 nm. The chemical structure of PEA was detected by infrared spectrum, which showed that electrospinning had no significant effect on PEA. X-ray diffraction spectrogram and differential scanning calorimetry revealed that the crystallinity of PEA was decreased after electrospinning. Mechanical property test demonstrated that the mean breaking strength and elongation at break of PEA nanofiber membrane with (0.50±0.05) mm thickness were (1.00±0.18) MPa, and (18.20±2.86)%, respectively. MTT results showed that the endothelial cells proliferated actively on the PEA nanofiber membrane, and presented good adhesive and growth status.
