Performance and clinical application of endovascular stent materials
10.3969/j.issn.1673-8225.2009.51.033
- VernacularTitle:血管内支架材料的性能及其临床应用评价
- Author:
Yanlin LI
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2009;13(51):10153-10156
- CountryChina
- Language:Chinese
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Abstract:
OBJECTIVE: To investigate clinical application of endovascular stents, to evaluate materials performance, and to study in-stent restenosis.METHODS: A computer-based online search was conducted in CNKI and Medline database with the key words of "endovascular stent, materials, application'' in both Chinese and English from 1960 to 2009. Among 67 articles, 31 references were included according to inclusion and exclusion criteria. All the included references were summarized based on application range of endovascular stent, stent materials, in-stent restenosis so as to investigate clinical application and performance of endovascular stent.RESULTS: Endovascular stent had been widely used to treat coronary atherosclerotic heart disease, intracranial aneurysm, symptomatic or non-symptomatic ischemic cerebrovascular disease, and peripheral angiopathy. Varying endovascular stent materials, such as metal, tissue-engineered, and drug-coating had remarkably therapeutic effect; in particular, biocompatibility and blood compatibility of drug-coating stent were superior to those of others. With the functional development of endovascular stent, more and more stents will be used for clinical therapy; however, restenosis and immunological rejection still remain unsolved.CONCLUSION: Endovascular stent has been widely used to treat varying cardio-cerebrovascular disease. Biocompatibility of drug-coating stent is superior to that of other stent materials. Endovascular stent with a great biocompatibility or Probucol-coating stent may reduce the incidence of restenosis.
