Vascular endothelial cell injury and repair mechanisms
10.3969/j.issn.1673-8225.2009.50.042
- VernacularTitle:血管内皮细胞损伤与修复的机制研究
- Author:
Jing LIU
;
Xiangyang ZHANG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2009;13(50):9997-10000
- CountryChina
- Language:Chinese
-
Abstract:
The vascular endothelial cells (VECs) are not only a mechanical barrier of blood cycle cells and vascular smooth muscle cells, but also largest and most important type of endocrine organs.Because of its mechanical barrier action It is highly susceptible to in vitro and in vivo a variety of physical and chemical factors in the injury; damaged VECsvascular endothelial cells, especially the disordered endocrine function, the inevitable imbalance to a variety of active substances secreted or related active substances, finally result in dysfunction of cardiovascular system.This article reviews many mechanisms underlying VECsvascular endothelial cell injury, investigates VECsvascular endothelial cell repair mechanisms, and study ways to protect and repair the injured VECsvascular endothelial cells, and improve the prognosis of vascular disease.
