Drug-resistance of coagulase negativeStaphylococcus isolated clinically in our hospital these years
- VernacularTitle:凝固酶阴性葡萄球菌分布及耐药变迁
- Author:
Xia LI
- Publication Type:Journal Article
- Keywords:
Staphylococcus;
Coagulase;
Drug Resistance,Bacterial
- From:International Journal of Laboratory Medicine
2008;29(12):1101-1103
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the distribution and the characteristics of drug resista-nce of coagulase negative Staphylococcus,and to provide the reference for properly choosi-ng antibiotic therapy of coagulase negative Staphylococcal infecs.Methods Contrasted 484 coagulase negative Staphylococcus(CNS) species isolated in hospital from 2001 to 2003 and 512 species from 2004 to 2007.Nosocomial CNS was identified and then drug resistance test was performed by K-B method,Nitrocefin method was utilized to detect β-lactamase.Clinical and Laboratory Standards Institute.Perfor-mance Standards forantimicro-bial susceptibility testing;Fifteenth information supplement.CLSI/NCCLS document M100-S17[J].Clinical and Laboratory Standards.Results The drug-resistant rate of.CNS to penicillin,erythromycin,oxacillin,amoxicillin/clavulanate,clindamycin,cepzolin,ceftriaxone and cefepime was high(>70%),whereas that to rifampin,nitrofurantoin,amikacin,tetracycline and trimetholvrim/sulfamethoxazole was low(<50%).No drug-resistant CNS strains to vancomyein were found.Conclusions,and no outstanding imparity from two groups.Conclusion The patterfi of resistance has changed greatly in the past 3 years.Clinical physicians should pay attention to properly choosing and using antibiotics.
