Roles and mechanism of tolerogenic dendritic cells in transplantation immunity
10.3969/j.issn.1673-8225.2009.53.028
- VernacularTitle:免疫耐受性树突状细胞在移植免疫中的作用及其分子机制
- Author:
Bimang FU
;
Anbin HU
;
Xiaoshun HE
;
Jie ZHANG
;
Jiefu HUANG
- Publication Type:Journal Article
- From:
Chinese Journal of Tissue Engineering Research
2009;13(53):10529-10532
- CountryChina
- Language:Chinese
-
Abstract:
It has been shown, however, that in terms of immune function, a transitional stage of dendritic cell maturation exists between immature myeloid dendritic cells (imDCs) and mature dendritic cells (DCs), which were named semimature dendritic cells (smDCs). Therefore, the theory that DCs can be classified as imDCs and mDCs has been challenged because of finding smDCs. SmDCs and imDCs are regarded as tolerogenic dendritc cells while what concrete mechanism taken by smDCs and imDCs in transplantation immunity has yet to know. The authors analyzed the important roles and the advanced molecular mechanism of smDCs and imDCs in transplantation immunity in order to update and widen understand underlying tolerogenic dendritic cells.
