Clinical Pathological Characteristics in Pancreatic Carcinoid
- VernacularTitle:胰腺类癌的临床和病理学特点分析
- Author:
Xiaosheng HE
;
Xiaojian WU
;
Yifeng ZOU
;
Xinjuan FAN
;
Jianping WANG
;
Ping LAN
- Publication Type:Journal Article
- Keywords:
carcinoid;
pancreas;
clinical pathological characteristics
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2010;31(1):114-117
- CountryChina
- Language:Chinese
-
Abstract:
[Objective] To explore the clinical pathological characteristics and treatment of pancreatic careinoid. [Methods] Eight patients with pancreatic careinoid were recruited between January in 1997 and December in 2007 for retrospective analysis which involved tumor markers, inanunohistostaining, accompanied with other tumors, misdiagnosis, metastasis, in-hospital mortality rate, and so on. The relevant literatures were simultaneously reviewed to comprehend the clinical pathological characteristics of pancreatic carcinoid. [Results] Tumor markers CEA, CA199, CA125, and CA72-4 in pancreatic carcinoid were 0%, 25%, 12.5%, and 0%, respectively. Specimen immanohistostaining Syn, CgA, NSE, and CK in pancreatic carcinoid were 25%, 62.5%, 75%, and 75%, respectively. Two pancreatic carcinoids were accompanied by other tumors in 8 cases. The misdiagnosis rate of pancreatic carcinoid (7/8) was markedly high. Pancreatic carcinoid possessed high metastasis (50%), high in-hospital mortality rate (37.5%) and low radical operation undergone (62.5%). [Conclusions] Pancrcatic carcinoid was accompanied with high misdiagnosis rate and poor prognosis. Routine sero-markers did not help discover pancreatic carcinoid early. The final diagnosis depended on specimen immunohistostaining with Syn, CgA, NSE, and CK.
