Advances in Research on Sumoylation of Breast Cancer-Related Proteins
- VernacularTitle:乳腺癌相关蛋白的类泛素化修饰研究进展
- Author:
Weiyi QIU
;
Qinong YE
- Publication Type:Journal Article
- Keywords:
Sumoylation;
ER signaling pathway;
Co-regulator;
Post-translational modifications;
Breast cancer
- From:
Acta Laboratorium Animalis Scientia Sinica
2010;18(1):87-90
- CountryChina
- Language:Chinese
-
Abstract:
Small ubiquitin-like modifiers (SUMO) are a family of proteins that modulate important functional properties,including protein interaction,subcellular localization,protein dimerization,DNA binding and/or transactivation of transcription factors.It has been suggested that SUMO proteins may play an important role in breast carcinogenesis by sumoylation of estrogen signaling proteins such as co-regulators,and breast cancer-related proteins.
