The actions of Bcl-2 on anti-ischemic neuron injury and the effects of anti-ischemic drugs on Bcl-2
- VernacularTitle:Bcl-2在缺血性神经细胞损伤中的作用及药物的影响
- Author:
Yuyang ZHANG
;
Linlin SHI
;
Donghai HAO
;
Lihong PAN
- Publication Type:Journal Article
- Keywords:
Bcl-2;
ischemia;
ischemia penumbra;
neuron;
apoptosis;
anti-injury mechanism
- From:
Chinese Pharmacological Bulletin
2010;26(1):21-24
- CountryChina
- Language:Chinese
-
Abstract:
Bcl-2 gene is the human homologous gene of anti-apoptotic gene Ced-9 in c-elegans, which can participate in regulations of cells apoptosis including suppression of neuronal apoptosis in cerebral ischemic penumbra.This review is about Bcl-2 anti-ischemic neuron injury, its possible mechanisms and the effects of anti-ischemic drugs on Bcl-2.
