The role of dopamine transporter in psychostimulant dependence
- VernacularTitle:多巴胺转运体在精神兴奋剂依赖中的作用
- Author:
Guangxiao WU
;
Ruibin SU
;
Jin LI
- Publication Type:Journal Article
- Keywords:
psychostimulant;
psychoactive substance;
dopamine;
DAT;
dependence;
reward
- From:
Chinese Pharmacological Bulletin
2010;26(2):141-143
- CountryChina
- Language:Chinese
-
Abstract:
Psychostimulant is a type of psychoactive substances that stimulate central and peripheral nervous system as well as induce drug dependence.A series of studies indicate that monoamine especially dopamine plays an important role in behavior and drug dependence,moreover,dopamine transporter(DAT)controls homeostasis of dopamine in neuron and transmission of dopamine pathways.Thus DAT might play an important role in the reward and behavioral stimulation of psychostimulant.
