Levofloxacin-Induced Achilles Tendinitis in a Young Adult in the Absence of Predisposing Conditions.
10.3349/ymj.2010.51.3.454
- Author:
Areum DUREY
1
;
Yong Soo BAEK
;
Jin Seok PARK
;
Kwangsoo LEE
;
Jeong Seon RYU
;
Jin Soo LEE
;
Moon Hyun CHEONG
Author Information
1. Department of Internal Medicine, Inha University School of Medicine, Incheon, Korea. ljinsoo@medimail.co.kr
- Publication Type:Case Report ; Research Support, Non-U.S. Gov't
- Keywords:
Fluoroquinolones;
tendinopathy;
Achilles tendinitis;
adverse reaction
- MeSH:
Achilles Tendon/*drug effects/pathology;
Adult;
Anti-Bacterial Agents/*adverse effects/therapeutic use;
Community-Acquired Infections/drug therapy;
Disease Susceptibility;
Humans;
Male;
Ofloxacin/*adverse effects/therapeutic use;
Pneumonia/drug therapy;
Tendinopathy/*chemically induced;
Young Adult
- From:Yonsei Medical Journal
2010;51(3):454-456
- CountryRepublic of Korea
- Language:English
-
Abstract:
Fluoroquinolones (FQs) represent a major class of antimicrobials that have a high potential as therapeutic agents. Although FQs are generally safe for the use as antimicrobials, they may induce tendinopathic complications such as tendinitis and tendon rupture. A number of factors have been suggested to further predispose a patient to such injuries. Hitherto, a few published cases on tendon disorders have implicated levofloxacin, a more recently introduced FQ. Here, we report a patient with levofloxacin-induced Achilles tendinitis, who exhibited no known predisposing factors. A 20-year-old man without any history of disease or medication presented with community-acquired pneumonia. Levofloxacin was administered and 3 days later, he complained of pain in the left Achilles tendon and revealed redness and swelling in the area. On suspecting Achilles tendinitis, levofloxacin treatment was discontinued, and the tendinitis subsequently improved. To our knowledge, this is the first case report on FQ-induced Achilles tendinitis in Korea.