The study of the cognitive impairment of middle-aged patients with type 2 diabetes mellitns
10.3969/j.issn.1006-6187.2010.01.008
- VernacularTitle:中年2型糖尿病患者认知功能障碍的研究
- Author:
Meixin LI
;
Shen MENG
;
Tong ZHANG
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus;
Cognition disorder;
Risk factor
- From:
Chinese Journal of Diabetes
2010;18(1):31-33
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the cognitive impairment of middle-aged patients with type 2 diabetes mellitus(T2DM). Methods Wechsler adult intelligence scale-Chinese revised edition (WATS-RC) was used as the tool to examine the cognitive function of middle-aged patients with T2DM and the healthy controls in 51 cases. The t-test was used to compare the differences in score between patients and the control group. The patients were divided into two groups with or without cognitive dysfunction. The logistic regression analysis was made for all the variables to confirm risk factors for the cognitive dysfunction in diabetes. Results The WAITS-RC scores of digit-symbol coding test and block design test were much lower(P<0.05) in diabetes versus control group. The other tests showed no significant difference. The cognitive function was negatively correlated with HbA_1>c and HOMA-IR by logistic regression analysis. Conclusions For middle-aged patients with type 2 diabetes, their cognitive functions such as learning ability, analysis and comprehensive capabilities are impaired. The cognitive function is closely related with HbA_1c and HOMA-IR.
