Research advance in role of ROS in cardioprotection offered by preconditioning or postconditioning
- VernacularTitle:活性氧介导预处理和后处理心肌保护效应研究的进展
- Author:
Ping XIN
;
Wei ZHU
;
Meng WEI
- Publication Type:Journal Article
- Keywords:
reactive oxygen species;
myocardial reperfusion injury;
preconditioning;
postconditioning
- From:
Journal of Shanghai Jiaotong University(medical Science)
2010;30(2):229-232
- CountryChina
- Language:Chinese
-
Abstract:
Reactive oxygen species(ROS)play an important role in the cardiac ischemic and reperfusion injury.However,accumulating evidences have demonstrated that ROS are pivotal components of redox signaling cascade relevant to cardioprotection induced by either preconditioning or postconditioning. In this review,the definition, source and detection methods of ROS are introduced.Besides,the role of ROS in the cardioprotection offered by preconditioning or postconditioning and the effects of either preconditioning or postconditioning on ROS are summarized.
