Chiral Separation and Enantiomerization of Triazole Pesticides
10.3724/SP.J.1096.2010.00237
- VernacularTitle:三唑农药的手性拆分及对映体的转化
- Author:
Zhaoyang LI
;
Yanchuan ZHANG
;
Qiaoling LI
;
Weixiao WANG
;
Jingyin LI
- Publication Type:Journal Article
- Keywords:
Triazole pesticides;
Chiral separation;
Enantiomerization;
Optical rotation;
Absolute configuration
- From:
Chinese Journal of Analytical Chemistry
2010;38(2):237-240
- CountryChina
- Language:Chinese
-
Abstract:
The chiral separation of three triazole pesticides, i.e. diniconazole, triadimefon and triadimenol was studied on a Chiralcel OJ-H and a Chiralcel OD-H HPLC chiral columns. The optical rotation quality of diniconazole and triadimefon enantiomers was measured and the absolute configurations of individual enan-)tiomers) were further concluded. On this basis, the absolute configurations of the four triadimenol stereoisomers were deduced via the reductive experiment of triadimefon to triadimenol. Furthermore, the chiral stability of the three triazole pesticides in organic solvents and buffer solutions was investigated. The results showed the obvious enantiomerization was observed as for triadimefon in methanol, ethanol and water, whereas dinicona-)zole) and triadimefon were chiral stable in organic solvents and water. The enantiomerization of triadimefon would be accelerated at higher temperature and in alkaline media.
